101856: Amphetamine induced dopamine release increases anxiety in individuals recovered from anorexia nervosa

Volume 45, Issue 2

About the Course:

Genetic, pharmacologic, and physiological data suggest that individuals with anorexia nervosa (AN) have altered striatal dopamine (DA) function.

Journal/Publisher:

Wiley Interscience Journal, International Journal of Eating Disorders

Publication Date:

March 2012

Authors

Ursula F. Bailer, MD; Rajesh Narendran, MD; W. Gordon Frankle, MD; Michael L. Himes, BS; Vikas Duvvuri, MD, PhD; Chester A. Mathis, PhD; Walter H. Kaye, MD

Recommended For:

This course is recommended for neuroscientists and psychologists who seek knowledge about the neurobiology of eating disorders.

Course Objectives:

  1. Identify the the major regions that comprise the reward pathways in the brain, and articulate how the study of reward neurocircuitry is relevant to the study of anorexia nervosa.

  2. Describe how dysregulation in these circuits may contribute to the persistence of anorexia nervosa.

  3. Discuss the value and limitations of sophisticated brain imaging techniques, such as positron emission tomography (PET) in the elucidation of the neurocircuitry underlying anorexia nervosa.

Exam Questions

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