Alzheimer Disease Biomarkers, Attentional Control and Semantic Memory Retrieval: Synergistic and Mediational Effects of Biomarkers on a Sensitive Cognitive Measure

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About the Course:

Considerable research has focused on cognitive performance characteristics which can best discriminate healthy aging from the earliest stages of Alzheimer disease. Of increasing importance is the identification of potential biomarkers that may help facilitate early detection of the disease. This study examined the utility of combining attentional control with semantic retrieval as a sensitive correlate of such biomarkers and used mediation analyses to examine possible mechanisms by which identified Alzheimer disease biomarkers influence cognition.

Publication Date:

Neuropsychology, 29(3) 2015


Andrew Aschenbrenner, PhD; David Balota, PhD; Chi-Shing Tse, PhD; Anne Fagan, PhD; David Holtzman, MD; Tammie Benzinger, MD, PhD; John Morris, MD

Recommended For:

This course is recommended for health care professionals, especially psychologists, counselors, social workers, and addiction counselors who seek knowledge about Alzheimer’s disease. It is appropriate for all levels of participants’ knowledge.

Course Objectives:

  1. Identify some of the bioimarkers for the prodromal stage of Alzheimer’s disease.

  2. Describe the biomarkers associated with cognitive changes secondary to Alzheimer’s disease.

  3. Identify neuropsychological instruments useful in measuring cognitive functioning.

  4. Discuss the salient results from this study.

Exam Questions

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